Stem Cells 
CAR-T 
AAV Delivery 
LVV Delivery 
Other Viral Vectors 
Nanoparticles Documentation System
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Car-T main: Goodbye Plasmids, Hello Synthetic oDNA
DNA is the foundation of nearly every advanced therapy modality, serving as both a therapeutic input and a critical starting material for mRNA, viral vectors, gene editing, and cell therapies.
proprietary synthetic DNA platform, providing optimized, plasmid-free linear DNA designed for performance and speed. With manufacturing capabilities in both the United States and Europe, this approach enables rapid access to high-purity starting material, flexible sequence design, and accelerated progression from research through GMP manufacturing — supporting faster development across modalities
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!! Title: oDNA TECH PAGE OPTION: ADAPTERS?
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The Traditional DNA Production Bottleneck
- 2-3 months production time
- Endotoxin u0026 other bacterial impurities
- Design limitations (e.g., length, polyA, antibiotic resistance genes)
- Scaling complexity through bacterial bioreactors
Artis’ Enzymatic oDNA Production
- Delivery in 2 weeks (RUO) u0026 3-4 weeks (GMP-grade)
- Application-specific formats to maximize GOI functionality
- Option to avoid pDNA altogether u0026 start with synthetic
- Gram-scale DNA, agnostic to length, complexity, or polyA
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Generic: Fully Synthetic DNA For Cleaner, More Controlled Starting Material
Truly synthetic oDNA — your gene of interest (GOI), enzymatically produced up to gram scale, free of biological contamination — is the next-generation starting material for every application in genetic medicine. Its unique synthetic double-stranded linear DNA design, consisting of only the GOI and adaptors, enables a library of design options that specifically fit your program or application.
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Flexible: What to learn more about our synthetic oDNA technology?
Artis is the first integrated platform combining proprietary enzymatic synthetic DNA production with advanced therapy development and GMP manufacturing, with operations in the US and EU. To read more about our next-generation synthetic DNA technology, originally developed at Artis-owned Syngoi Technologies, visit Syngoi’s website.
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Extended Stability
Improved DNA stability within cytoplasm
Efficient Transcription
Targeted T7-RNAP structure guided adaptors
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!! Application-Based DNA Adaptors Tailor GOI Function to End Goals
Extended Stability
Improved DNA stability within cytoplasm
Efficient Transcription
Targeted T7-RNAP structure guided adaptors
Cell Type Targeting
Some other description about this
High Expression
something more about this
Nuclear Translocation
more info about what we mean
Release from Delivery Vectors
more info
Tailored Immunogenic Responses
additional info
Function-guided adapters improve performance
Structure-guided adaptor design, based on T7 RNA polymerase crystal structure, results in higher transcription rate and efficiency.
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RNA-based vaccines
RNA-based therapeutics
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RNA-based vaccines
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